| |
What
are the clinical findings in acute “Alcohols” intoxication case
? |
 |
| |
Methanol
( 甲醇 )
Ethanol ( 乙醇)
Ethylene glycol ( 乙二醇 )
Isopropyl alcohol ( 異丙醇 )
|
|
|
| |
Clinical
findings (1) |
|
| |
| Methanol:
(12-18 hrs onset) |
| CNS
depression |
Visual
disturbances |
| Abd
pain/ Nausea |
Retinal
edema |
| Optic
disk hyperemia |
Headache |
| Seizures |
Black
feces |
| Anion
& Osmolalgaps |
Metabolic acidosis |
| Ethanol
|
| Slurred
speech |
Disinhibited
behavior |
| CNS
depression |
Altered
coordination |
| Anion
& Osmolal gaps |
Respiratory
depression |
| Ethylene
glycol |
| Stage
1< 12 hrs |
CNS:
CNS depression, slurred speech, ataxia, nystagmus,
convulsions, coma, decreased light reflex, decreased
visual acuity, optic disk blurring, papilledema |
Stage
2
12-24 hrs |
Cardiopulmonary:
HTN, tachycardia, pulmonary edema, hypocalcemia,
dysrhythmia, myositis.
|
Stage
3
24-72 hrs
|
Renal:
Flank pain, ATN, ARF, hematuria, protenuria, |
| Isopropylalcohol |
CNS
depression
|
Respiratory
depression |
| Hypotension |
Ketonemia/
ketonuria |
| Nausea/
Vomiting |
Acute
tubular necrosis |
Significant
osmolal gap
No anion gap |
Rhabdomyolysis |
|
|
|
|
