藥品名稱
drug name | Ipratropium (Ipratran inhalation solu./ Atrovent(舊名), 益撲喘吸入液) 500 mcg/2 mL/pill |
| 藥檔狀態 | 使用中 |
成 份
Ingredient | Ipratropium Bromide |
| 單位含量 | 500 mcg/2 mL/pill |
| Dosage Forms | Nebuliser solution, as bromide: 0.25 mg/mL (2 mL) |
| 外觀描述 | 無色澄明液體 外用/吸入 |
| Appearance | external/inhaler |
標 示
outward | 管狀塑膠封裝 |
廠商名稱
Manufacturer | 信東生技股份有限公司 |
製 造 商
Manufacturer | 麥迪森醫藥股份有限公司桃園廠, TAIWAN |
字 號
Product ID | 衛署藥製字第043943號 |
藥理分類
Pharmacologic Category | Respiratory Agents/ Respiratory Inhalant Products/ Anticholinergics |
作用機轉
Mechanism of action | Blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation; local application to nasal mucosa inhibits serous and seromucous gland secretions. |
| 用途/適應症 | 氣管擴張劑 |
| Use |
Anticholinergic bronchodilator used in bronchospasm associated with COPD, bronchitis, and emphysema
|
衛福部核准適用症狀
MOHW approved indications |
慢性阻塞性支氣管炎、支氣管氣喘。
|
| Dose |
Adults:
Asthma exacerbation, acute: 0.5 mg(500 mcg)every 20 minutes for 3 doses, then as needed. Note: Should be given in combination with a short-acting beta-adrenergic agonist.
Bronchospasm associated with COPD: 0.5 mg(500 mcg)(one unit-dose vial) TID-QID with doses 6-8 hours apart
Pediatrics: Asthma exacerbation, acute:
Children ≦12 years: 0.25-0.5 mg(250-500 mcg) every 20 minutes for 3 doses, then as needed.
Note: Should be given in combination with a short-acting beta-adrenergic agonist.
Children >12 years: Refer to adult dosing.
|
懷孕分級
Pregnancy Risk Factor |
B
Lactation: Excretion in breast milk unknown/use caution
|
| 禁忌症 |
已知對阿托平或本劑中其他成分有過敏反應者，忌用本藥。
|
| Contraindications |
Hypersensitivity to ipratropium, atropine (and its derivatives), or any component of the formulation.
|
| 常見副作用 | 上呼吸道感染、支氣管炎、鼻竇炎、呼吸困難、頭痛。 |
| Common adverse drug reactions | Upper respiratory tract infection, bronchitis, sinusitis, dyspnea and headache. |
| Adverse Reactions |
>10%:
Respiratory: Upper respiratory tract infection (9% to 34%), bronchitis (10% to 23%), sinusitis (1% to 11%)
1% to 10%:
Cardiovascular: Chest pain (3%), palpitation
Central nervous system: Headache (6% to 7%), dizziness (2% to 3%)
Gastrointestinal: Dyspepsia (1% to 5%), nausea (4%), xerostomia (2% to 4%)
Genitourinary: Urinary tract infection (2% to 10%)
Neuromuscular & skeletal: Back pain (2% to 7%)
Respiratory: Dyspnea (7% to 10%), rhinitis (2% to 6%), cough (3% to 5%), pharyngitis (4%), bronchospasm (2%), sputum increased (1%)
Miscellaneous: Flu-like syndrome (4% to 8%)
|
監測
Monitoring |
|
| 警語與注意事項 | 吸入劑；不可口服。1071009"台灣百齡佳殷格翰"換廠為"信東" |
| Warnings & precautions | Respiratory Inhalant Products. |
| 針劑溶解條件 |
|
| 針劑稀釋條件 |
1.每1 mL的單一劑量可用生理食鹽水稀釋至2-4mL。
2.2 mL單一劑量可用生理食鹽水稀釋至4-8 mL使用。(101009仿單資料)
|
| 針劑不相容性 |
Ipratropium Bromide單一劑量吸入液不可與disodium cormoglycate吸入液加在相同的噴霧裝置內使用。(1071009仿單資料)
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| 針劑施打條件 |
|
| 針劑保存安定性 |
小瓶打開後應立即使用。
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最近修改日期時間
Updated | 10/9/2018 4:30:09 PM |